Print Overview Perimenopause means around menopause and refers to the time during which your body makes the natural transition to menopause, marking the end of the reproductive years. Perimenopause is also called the menopausal transition. Women start perimenopause at different ages. You may notice signs of progression toward menopause, such as menstrual irregularity, sometime in your 40s. But some women notice changes as early as their mids. The level of estrogen — the main female hormone — in your body rises and falls unevenly during perimenopause.
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